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The Academy of American Poets is the largest membership-based nonprofit organization fostering an appreciation for contemporary poetry and supporting American poets. For over three generations, the Academy has connected millions of people to great poetry through programs such as National Poetry Month, the largest literary celebration in the world;, the Academy’s popular website; American Poets, a biannual literary journal; and an annual series of poetry readings and special events. Since its founding, the Academy has awarded more money to poets than any other organization.

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Are you currently taking part in a research study?
Has someone asked you to take part in a research study?
Are you thinking about taking part in a research study?

If you answered YES to any of the questions, please read the following information carefully.

You need to know your rights as a research participant (or potential participant) so you can make sure that you are being treated fairly. Those rights include, but are not limited to, the following:

1. You have the right to say no.

You have the right to refuse to join a study. In fact, no one is allowed to perform research with you unless you have given your permission and signed an informed consent document (sometimes just called a “consent form”). The purpose of an informed consent document is to help you understand everything that will (or could) happen during the study in which you are being asked to participate. You do not give up any of your legal rights when you sign the informed consent document and join a study.

2. You have the right to quit.

You have the right to stop participating in a study, for any reason, and at any time, without losing any of your medical care options.

3. You have the right to know why.

You have the right to know the purpose of the research study that you are being asked to join.

4. You have the right to know the risks.

You have the right to know all of the risks that you are taking if you choose to take part in a study (as well as anything that might be of benefit to you).

5. You have the right to know what else you can do.

You have the right to be told about all other medical options available to you, if you choose not to participate in the study. You have the right to be told if there are any medical options available that may be better for you than participating in the study.

6. You have the right to ask questions and have them answered.

You have the right to ask any question about the study before you join, and you have the right to ask questions as the study continues and after it ends. You also have the right to have all of your questions answered to your satisfaction.

The FDA suggests you ask the following questions to a study doctor before you join a study:

7. You have the right to take your time.

You have the right to take plenty of time, without anyone pressuring you, to decide whether or not to join a study.

8. You have the right to talk to others.

You have the right to discuss with your doctor, your family, and your friends, whether or not you should join a study. You have the right to receive a copy of the informed consent document to help you make your decision.

Science : 604-607

Methylation of the bacterial ribosome by two methyltransferases proceeds by an unusual radical mechanism.


Structural studies of viperin, an antiviral radical SAM enzyme
Radical new paradigm for heme degradation in Escherichia coli O157:H7
Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA
Identification and characterization of functional homologs of nitrogenase cofactor biosynthesis protein NifB from methanogens
Proteomic Analysis of Cold Stress Responses in Banana Leaves
Potential of Novel Antimicrobial Peptide P3 from Bovine Erythrocytes and Its Analogs To Disrupt Bacterial Membranes In Vitro and Display Activity against Drug-Resistant Bacteria in a Mouse Model
Radical S-Adenosyl-L-methionine Chemistry in the Synthesis of Hydrogenase and Nitrogenase Metal Cofactors
Spore Photoproduct Lyase: The Known, the Controversial, and the Unknown
Mechanistic Diversity of Radical S-Adenosylmethionine (SAM)-dependent Methylation
Identification of a Unique Radical S-Adenosylmethionine Methylase Likely Involved in Methanopterin Biosynthesis in Methanocaldococcus jannaschii
The mthA Mutation Conferring Low-Level Resistance to Streptomycin Enhances Antibiotic Production in Bacillus subtilis by Increasing the S-Adenosylmethionine Pool Size
Distinction between the Cfr Methyltransferase Conferring Antibiotic Resistance and the Housekeeping RlmN Methyltransferase
X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification
Biosynthesis of the Iron-Molybdenum Cofactor of Nitrogenase
The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy
A Radical Route for Nitrogenase Carbide Insertion
Radical SAM-Dependent Carbon Insertion into the Nitrogenase M-Cluster
The Order Bacillales Hosts Functional Homologs of the Worrisome cfr Antibiotic Resistance Gene
Resistance to Linezolid Caused by Modifications at Its Binding Site on the Ribosome
Complex Biotransformations Catalyzed by Radical S-Adenosylmethionine Enzymes
Structural Basis for Methyl Transfer by a Radical SAM Enzyme
The Two Faces of SAM


6 July 2018

Vol 361, Issue 6397


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NEW YORK (CBSNewYork) — Over the past few months, commutes on the rails, roads, and in the air have faced worse than ever delays and cancellations.


Worse than the angst of being late for work or a missed appointment, the stress of it all can literally be making you sick.

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Commuter Jennifer Tang said she’s endured plenty of subway delays, but says one in particular — a power outage in January — drove her to the breaking point.

“I was mentally and physically exhausted, I had this terrible shaking inside of me,” she told CBS2.

A few weeks later, she says a doctor took her blood pressure and told her it was very high. Dr. Susanne Cooperman is a psychoanalyst who treats patients with extreme symptoms brought on by stressful commutes.

“The anxiety builds and builds, the adrenaline courses through your veins,” she said. “It affects every cell in your body. You can become sick physically, but also emotionally.”

Dr. Cooperman adds it also can impact sleep and concentration.

“It’s more toxic to your body than PTSD,” she said.

Kate Lawrence has what’s known as “avoidance fears” and has completely stopped taking the train.

“My legs are a little shaky, my heart is racing,” she said.

For Lawrence, Dr. Cooperman recommends taking small, slow steps to get used to it.

“So take a friend,” she said. “Try to drive the subway for just one stop.”

Even CBS Travel Editor Peter Greenberg has had his share of commuter stress.

“Whether it’s planes, trains, automobiles, any type of transportation. The stress level goes up,” he said. “So it’s not a matter of whether or not you’re going to get stressed, but how you’re going to manage it.”

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